Mode of Action of Morganocin 174

Mobilization of morganocin 174 plasmid and kinetics of morganocin production in Proteus and Escherichia coli hosts.

Morganocin 174 is coded by a plasmid, Mor174. The plasmid is not self-transmissible but may be mobilized by resistance factor R772. Morganocin synthesis in all Proteus and Providencia strains carrying Mor174 was characterized by a longer lag period after induction and higher titers than in Escherichia coli B(Mor174). The low titers obtained in E. coli B(Mor174) are due to a heatstable inhibitor...

evolution and mode of action of pulsed radiofrequency

Mode of Action

Being impermeable to folic acid, many bacteria must rely on their ability to synthesise folate from PABA, Pteridine, and glutamate in contrast the mammalian in cells cannot synthesise folic acid and must obtain preformed folate as a vitamin in their diet. The sulphonamides are structurally similar to PABA, the sulphonamides competitively inhibit dihydropteroate synthetase, the enzyme that catal...

Mode of action of tomaymycin.

The mode of action of tomaymycin (TM) which is a new antibiotic with antitumor activity was studied. Inhibition of the incorporation of labeled precursors into the acid-insoluble fraction of Bacillus subtilis cells indicated that TM inhibits nucleic acids biosynthesis, while having relatively little effect on protein synthesis. TMdisplaced methyl green (MG) from a MG-DNA complex and a TM-DNA co...

Mode of action of antibiotics

An antibiotic is an organic substance produced by a 1)living organism which inhibits the growth of or kills some ,, other living organism. Two. of the more important antibiotic .that have been studied are penicillin and streptomycin. Although three structural formulae for penicillin have been presented, this antibiotic is generally thought of as Ia ring condensation of two amino acids: alanine ...